Rare Endocrinology News
5 Facts you should know about
Primary hyperoxaluria type 1 (PH1)
1
The majority of individuals with PH1 present in childhood or early adolescence, usually with symptomatic nephrolithiasis and normal or reduced kidney function
2
Common symptoms include the urolithiasis, nephrolithiasis, and progressive nephrocalcinosis
3
PH type I is the most severe and most common of the three types - it is estimated to account for 70 to 80% of all diagnosed PH patients
4
Up to 50% of adults are diagnosed following progression to end-stage kidney disease (ESKD)
5
Chronic, recurrent stone formation and the accumulation of calcium oxalate in kidney tissue can cause chronic kidney disease, which can ultimately progress to kidney failure
Rare Endocrinology News
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