Rare Endocrinology News
Disease Profile
Adolescent idiopathic scoliosis
Prevalence estimates on Rare Medical Network websites are calculated based on data available from numerous sources, including US and European government statistics, the NIH, Orphanet, and published epidemiologic studies. Rare disease population data is recognized to be highly variable, and based on a wide variety of source data and methodologies, so the prevalence data on this site should be assumed to be estimated and cannot be considered to be absolutely correct.
#N/A
Age of onset
#N/A
ICD-10
#N/A
Inheritance
Autosomal dominant A pathogenic variant in only one gene copy in each cell is sufficient to cause an autosomal dominant disease.
Autosomal recessive Pathogenic variants in both copies of each gene of the chromosome are needed to cause an autosomal recessive disease and observe the mutant phenotype.
X-linked
dominant X-linked dominant inheritance, sometimes referred to as X-linked dominance, is a mode of genetic inheritance by which a dominant gene is carried on the X chromosome.
dominant X-linked dominant inheritance, sometimes referred to as X-linked dominance, is a mode of genetic inheritance by which a dominant gene is carried on the X chromosome.
X-linked
recessive Pathogenic variants in both copies of a gene on the X chromosome cause an X-linked recessive disorder.
recessive Pathogenic variants in both copies of a gene on the X chromosome cause an X-linked recessive disorder.
Mitochondrial or multigenic Mitochondrial genetic disorders can be caused by changes (mutations) in either the mitochondrial DNA or nuclear DNA that lead to dysfunction of the mitochondria and inadequate production of energy.
Multigenic or multifactor Inheritance involving many factors, of which at least one is genetic but none is of overwhelming importance, as in the causation of a disease by multiple genetic and environmental factors.
Not applicable
Other names (AKA)
Idiopathic adolescent scoliosis
Summary
Adolescent idiopathic
Symptoms
Scoliosis can occur as a feature of other conditions, including a variety of genetic
Cause
Researchers suspect that many
Treatment
Detailed information about these treatment options can be accessed through the Scoliosis Research Society.
Organizations
Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services. Many develop patient-centered information and are the driving force behind research for better treatments and possible cures. They can direct you to research, resources, and services. Many organizations also have experts who serve as medical advisors or provide lists of doctors/clinics. Visit the group’s website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.
Organizations Supporting this Disease
-
National Scoliosis Foundation
5 Cabot Place
Stoughton, MA 02072
Toll-free: 1-800-NSF-MYBACK (800-673-6922)
Fax: 781-341-8333
E-mail: [email protected]
Website: https://www.scoliosis.org/ -
Scoliosis Research Society (SRS)
555 East Wells Street, Suite 1100
Milwaukee, WI 53202-3823
Telephone: +1-414-289-9107
Fax: +1-414-276-3349
E-mail: [email protected]
Website: https://www.srs.org/
Learn more
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
Where to Start
- Genetics Home Reference contains information on Adolescent idiopathic scoliosis. This website is maintained by the National Library of Medicine.
References
- Adolescent idiopathic scoliosis. Genetics Home Reference (GHR). September 2013; https://ghr.nlm.nih.gov/condition/adolescent-idiopathic-scoliosis. Accessed 11/10/2014.
- Idiopathic Scoliosis: Adolescents: Treatment. Scoliosis Research Society. 2014; https://www.srs.org/patient_and_family/scoliosis/idiopathic/adolescents/treatment.htm. Accessed 11/10/2014.
- Frequently Asked Questions. Genetic and Rare Diseases Information Center. https://rarediseases.info.nih.gov/about-gard/pages/31/frequently-asked-questions. Accessed 3/6/2016.
Rare Endocrinology News